Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and inflammation associated with various conditions, such as osteoarthritis, rheumatoid arthritis, and menstrual cramps.
Meloxicam oral tablets are available in strengths of 7.5 mg and 15 mg. The usual starting dose is 7.5 mg once daily. If needed, your doctor may increase the dose to 15 mg once daily.
It is important to take meloxicam with food or milk to reduce the risk of stomach upset. The medication should be taken at the same time each day to maintain a consistent level of the drug in your system.
As with all NSAIDs, meloxicam can cause side effects such as stomach upset, diarrhea, headache, dizziness, and skin rash. It may also increase the risk of serious cardiovascular events, such as heart attack or stroke, especially if taken for long periods of time or in high doses.
It is important to use meloxicam only as directed by your healthcare provider and to report any unusual symptoms or side effects immediately.
Highlights for meloxicam
Here are some key highlights for meloxicam:
- Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation associated with various conditions, such as osteoarthritis, rheumatoid arthritis, and menstrual cramps.
- Meloxicam is available in oral tablet form in strengths of 7.5 mg and 15 mg.
- The usual starting dose of meloxicam is 7.5 mg once daily. If needed, your doctor may increase the dose to 15 mg once daily.
- Meloxicam should be taken with food or milk to reduce the risk of stomach upset. It should also be taken at the same time each day to maintain a consistent level of the drug in your system.
- Meloxicam can cause side effects such as stomach upset, diarrhea, headache, dizziness, and skin rash. It may also increase the risk of serious cardiovascular events, such as heart attack or stroke, especially if taken for long periods of time or in high doses.
- You should use meloxicam only as directed by your healthcare provider and report any unusual symptoms or side effects immediately.
- Meloxicam should not be used in late pregnancy as it may harm the unborn baby. It should also be used with caution in patients with a history of stomach ulcers or bleeding, high blood pressure, or heart failure.
- Alcohol consumption should be avoided while taking meloxicam, as it may increase the risk of stomach bleeding.
- Meloxicam may interact with other medications, so it is important to inform your healthcare provider of all the medications you are taking, including prescription, over-the-counter, and herbal products.
- Meloxicam should be stored at room temperature, away from moisture and heat.
What is meloxicam?
Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation associated with various conditions, such as osteoarthritis, rheumatoid arthritis, and menstrual cramps. It works by reducing the levels of certain hormones in the body that cause pain and inflammation.
Meloxicam is available in oral tablet form and is typically taken once a day with food or milk to reduce the risk of stomach upset. The medication is available in strengths of 7.5 mg and 15 mg.
As with all NSAIDs, meloxicam can cause side effects such as stomach upset, diarrhea, headache, dizziness, and skin rash. It may also increase the risk of serious cardiovascular events, such as heart attack or stroke, especially if taken for long periods of time or in high doses.
It is important to use meloxicam only as directed by your healthcare provider and to report any unusual symptoms or side effects immediately. Additionally, meloxicam should not be used in late pregnancy as it may harm the unborn baby. It should also be used with caution in patients with a history of stomach ulcers or bleeding, high blood pressure, or heart failure.
Why it’s used
Meloxicam is used to treat pain and inflammation associated with various conditions, including:
- Osteoarthritis: a condition that causes joint pain and stiffness due to the breakdown of cartilage in the joints.
- Rheumatoid arthritis: an autoimmune disorder that causes joint inflammation, pain, and stiffness.
- Juvenile rheumatoid arthritis: a type of arthritis that affects children under the age of 16.
- Ankylosing spondylitis: a type of arthritis that affects the spine and can cause stiffness and pain in the back.
- Menstrual cramps: pain and discomfort that occur before or during menstruation.
- Other conditions that cause pain and inflammation, such as gout, bursitis, and tendonitis.
Meloxicam is an NSAID that works by reducing the levels of certain hormones in the body that cause pain and inflammation. It is available in oral tablet form and is typically taken once a day with food or milk to reduce the risk of stomach upset.
It is important to use meloxicam only as directed by your healthcare provider and to report any unusual symptoms or side effects immediately. Additionally, meloxicam should not be used in late pregnancy as it may harm the unborn baby. It should also be used with caution in patients with a history of stomach ulcers or bleeding, high blood pressure, or heart failure.
How it works
Meloxicam works by inhibiting the production of prostaglandins, which are hormone-like substances that contribute to pain and inflammation in the body. Prostaglandins are produced in response to injury or inflammation and are responsible for causing swelling, pain, and fever.
Meloxicam blocks the action of an enzyme called cyclooxygenase (COX), which is responsible for the production of prostaglandins. By blocking COX, meloxicam reduces the production of prostaglandins and, in turn, reduces inflammation, swelling, and pain.
Meloxicam is a selective COX-2 inhibitor, which means it primarily targets the COX-2 enzyme that is responsible for producing prostaglandins in response to inflammation. This makes meloxicam less likely to cause gastrointestinal side effects compared to non-selective COX inhibitors, which inhibit both COX-1 and COX-2 enzymes.
Overall, meloxicam helps to alleviate pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and menstrual cramps by reducing the production of prostaglandins in the body.
Meloxicam side effects
Meloxicam may cause side effects in some people. Some common side effects include:
- Stomach upset, including nausea, vomiting, and abdominal pain.
- Diarrhea or constipation.
- Dizziness or headache.
- Skin rash or itching.
Less commonly, meloxicam can cause more serious side effects. These may include:
- Allergic reaction, including hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
- Chest pain or shortness of breath.
- Signs of stomach bleeding, such as black, tarry stools, blood in the urine or vomit, or abdominal pain.
- Signs of liver damage, such as yellowing of the skin or eyes, dark urine, or persistent nausea or vomiting.
- Signs of kidney problems, such as decreased urine output, swelling of the feet or ankles, or persistent fatigue or weakness.
- High blood pressure or heart failure.
- Increased risk of serious cardiovascular events such as heart attack or stroke, especially when used for long periods of time or in high doses.
It is important to seek medical attention immediately if you experience any of these symptoms or if you have any concerns about possible side effects. Additionally, inform your healthcare provider if you are taking any other medications, including prescription, over-the-counter, or herbal products, as they may interact with meloxicam and increase the risk of side effects.
More common side effects
The more common side effects of meloxicam include:
- Stomach upset, including nausea, vomiting, and abdominal pain.
- Diarrhea or constipation.
- Dizziness or headache.
- Skin rash or itching.
- Gas or bloating.
- Indigestion or heartburn.
- Mild stomach cramps.
These side effects usually go away on their own as your body adjusts to the medication. If they persist or become bothersome, contact your healthcare provider.
It is important to note that the risk of serious side effects increases with long-term use of meloxicam and with high doses. Therefore, it is important to take meloxicam only as prescribed and to follow your healthcare provider’s instructions carefully. If you experience any unusual symptoms or side effects while taking meloxicam, contact your healthcare provider immediately.
Serious side effects
Serious side effects of meloxicam can occur, although they are rare. If you experience any of the following symptoms, seek immediate medical attention:
- Allergic reaction, including hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
- Chest pain or tightness.
- Signs of stomach bleeding, such as black, tarry stools, blood in the urine or vomit, or severe abdominal pain.
- Signs of liver damage, such as yellowing of the skin or eyes, dark urine, or persistent nausea or vomiting.
- Signs of kidney problems, such as decreased urine output, swelling of the feet or ankles, or persistent fatigue or weakness.
- High blood pressure or heart failure.
- Increased risk of serious cardiovascular events such as heart attack or stroke, especially when used for long periods of time or in high doses.
Other serious side effects that can occur with meloxicam include:
- Severe skin reactions, such as Stevens-Johnson syndrome or toxic epidermal necrolysis, which can cause skin blistering and peeling.
- Blood disorders, such as anemia, leukopenia, or thrombocytopenia, which can cause fatigue, weakness, and increased risk of infection or bleeding.
- Fluid retention, which can cause swelling of the legs, ankles, or feet, or shortness of breath.
It is important to report any unusual symptoms or side effects to your healthcare provider immediately.
Meloxicam may interact with other medications
Yes, meloxicam may interact with other medications, including prescription, over-the-counter, and herbal products. Some medications that may interact with meloxicam include:
- Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen, which can increase the risk of stomach bleeding.
- Blood thinners, such as warfarin, which can increase the risk of bleeding.
- Diuretics, such as furosemide, which can decrease the effectiveness of meloxicam and increase the risk of kidney problems.
- ACE inhibitors, such as lisinopril, which can decrease the effectiveness of meloxicam and increase the risk of kidney problems.
- Lithium, which can increase the risk of lithium toxicity.
- Methotrexate, which can increase the risk of methotrexate toxicity.
- Corticosteroids, such as prednisone, which can increase the risk of stomach bleeding and other side effects.
It is important to inform your healthcare provider of all medications you are taking, including prescription, over-the-counter, and herbal products, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Antidepressants and anxiety drugs
Antidepressants and anxiety drugs may interact with meloxicam, and caution should be used when taking these medications together. Some antidepressants and anxiety drugs that may interact with meloxicam include:
- Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine or sertraline, which can increase the risk of bleeding.
- Serotonin-norepinephrine reuptake inhibitors (SNRIs), such as duloxetine or venlafaxine, which can increase the risk of bleeding.
- Benzodiazepines, such as alprazolam or lorazepam, which can increase the sedative effects of meloxicam.
- Tricyclic antidepressants (TCAs), such as amitriptyline or nortriptyline, which can increase the risk of bleeding.
- Monoamine oxidase inhibitors (MAOIs), such as phenelzine or tranylcypromine, which can increase the risk of serotonin syndrome when taken with meloxicam.
It is important to inform your healthcare provider of all medications you are taking, including antidepressants and anxiety drugs, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Corticosteroids
Corticosteroids and meloxicam may interact and caution should be used when taking these medications together. Corticosteroids, such as prednisone or dexamethasone, can increase the risk of stomach bleeding and other side effects when taken with meloxicam. Additionally, corticosteroids can increase the risk of high blood pressure and fluid retention, which can worsen with the use of meloxicam.
If you are taking corticosteroids and meloxicam together, your healthcare provider may monitor you closely for side effects, such as stomach bleeding, high blood pressure, or fluid retention. It is important to inform your healthcare provider of all medications you are taking, including corticosteroids, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Cancer drug
There is limited information available on the potential interaction between meloxicam and cancer drugs, as this can vary depending on the specific cancer drug and individual patient factors. In general, caution should be used when taking meloxicam with cancer drugs, and your healthcare provider should be consulted before starting or changing any medications.
Some cancer drugs may increase the risk of bleeding when taken with meloxicam, such as anticoagulants like warfarin or heparin. Additionally, some cancer drugs may increase the risk of kidney problems, which can worsen with the use of meloxicam. In some cases, the combination of cancer drugs and meloxicam may be necessary and safe, but this should be determined by a healthcare provider on an individual basis.
It is important to inform your healthcare provider of all medications you are taking, including cancer drugs, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Transplant drug
Caution should be used when taking meloxicam with transplant drugs, as interactions can vary depending on the specific transplant drug and individual patient factors. In general, meloxicam may interact with transplant drugs and may increase the risk of kidney problems or other side effects.
Some transplant drugs, such as cyclosporine or tacrolimus, may decrease the effectiveness of meloxicam and increase the risk of kidney problems. Other transplant drugs, such as mycophenolate or azathioprine, may increase the risk of bleeding when taken with meloxicam. In some cases, the combination of transplant drugs and meloxicam may be necessary and safe, but this should be determined by a healthcare provider on an individual basis.
It is important to inform your healthcare provider of all medications you are taking, including transplant drugs, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Disease-modifying antirheumatic drug
Disease-modifying antirheumatic drugs (DMARDs) and meloxicam may interact and caution should be used when taking these medications together. DMARDs, such as methotrexate or sulfasalazine, are often used to treat rheumatoid arthritis and other autoimmune diseases.
Meloxicam should be used with caution when taken with DMARDs, as they may increase the risk of gastrointestinal bleeding or other side effects. Additionally, some DMARDs, such as methotrexate, may increase the risk of liver problems when taken with meloxicam.
If you are taking DMARDs and meloxicam together, your healthcare provider may monitor you closely for side effects, such as stomach bleeding, liver problems, or other adverse reactions. It is important to inform your healthcare provider of all medications you are taking, including DMARDs, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Anticoagulant/blood thinner
Anticoagulants, such as warfarin, heparin, or dabigatran, and meloxicam may interact and caution should be used when taking these medications together. Both anticoagulants and meloxicam can increase the risk of bleeding, and taking them together can further increase this risk.
If you are taking anticoagulants and meloxicam together, your healthcare provider may monitor you closely for signs of bleeding, such as easy bruising, red or black stools, or bleeding gums. It is important to inform your healthcare provider of all medications you are taking, including anticoagulants, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
It is also important to note that nonsteroidal anti-inflammatory drugs (NSAIDs) like meloxicam should be used with caution in patients taking anticoagulants, as they can increase the risk of bleeding. If you are taking anticoagulants, you should discuss with your healthcare provider which pain relievers or anti-inflammatory drugs are safest for you to use.
Bipolar disorder medication
Bipolar disorder medications, such as lithium, valproic acid, or lamotrigine, may interact with meloxicam and caution should be used when taking these medications together.
Meloxicam may decrease the effectiveness of bipolar disorder medications and increase the risk of lithium toxicity, which can lead to serious side effects. Additionally, bipolar disorder medications may increase the risk of kidney problems when taken with meloxicam.
If you are taking bipolar disorder medications and meloxicam together, your healthcare provider may monitor you closely for signs of lithium toxicity, such as confusion, tremors, or seizures. It is important to inform your healthcare provider of all medications you are taking, including bipolar disorder medications, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Blood pressure drugs
Blood pressure drugs, such as ACE inhibitors, angiotensin receptor blockers (ARBs), or diuretics, and meloxicam may interact and caution should be used when taking these medications together.
Meloxicam may decrease the effectiveness of blood pressure drugs and may increase the risk of kidney problems or other side effects. Additionally, blood pressure drugs may increase the risk of kidney problems when taken with meloxicam.
If you are taking blood pressure drugs and meloxicam together, your healthcare provider may monitor you closely for signs of kidney problems, such as changes in urine output or swelling in the legs or feet. It is important to inform your healthcare provider of all medications you are taking, including blood pressure drugs, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Diuretics (water pills)
Diuretics, also known as water pills, and meloxicam may interact and caution should be used when taking these medications together.
Meloxicam may decrease the effectiveness of diuretics and increase the risk of kidney problems or other side effects. Additionally, diuretics may increase the risk of kidney problems when taken with meloxicam.
If you are taking diuretics and meloxicam together, your healthcare provider may monitor you closely for signs of kidney problems, such as changes in urine output or swelling in the legs or feet. It is important to inform your healthcare provider of all medications you are taking, including diuretics, before starting meloxicam. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider.
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Meloxicam belongs to a class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs), which also includes aspirin, ibuprofen, and naproxen. Caution should be used when taking NSAIDs together with meloxicam, as they can increase the risk of side effects, particularly stomach ulcers and bleeding.
If you are taking other NSAIDs along with meloxicam, your healthcare provider may adjust your dose or monitor you more closely for side effects. Additionally, do not start, stop, or change the dosage of any medications without first consulting your healthcare provider. It is important to inform your healthcare provider of all medications you are taking, including over-the-counter NSAIDs, before starting meloxicam.
How to take meloxicam
Meloxicam should be taken exactly as prescribed by your healthcare provider. The medication is typically taken once daily, with or without food.
It is important to take meloxicam with a full glass of water and to avoid lying down for at least 10 minutes after taking it to reduce the risk of stomach upset.
Do not crush, chew, or break the meloxicam tablet, as this can cause the medication to be released too quickly into your system. Swallow the tablet whole.
If you miss a dose of meloxicam, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Do not stop taking meloxicam without first consulting your healthcare provider, even if you start to feel better. Stopping the medication suddenly can lead to withdrawal symptoms or a worsening of your condition.
Forms and strengths
Meloxicam is available in several forms and strengths, including:
- Oral tablets: Meloxicam tablets are available in strengths of 7.5 mg and 15 mg.
- Oral suspension: Meloxicam oral suspension is available in a strength of 7.5 mg/5 mL.
- Topical gel: Meloxicam topical gel is available in a strength of 1.5%.
The appropriate form and strength of meloxicam will depend on your medical condition, age, and other factors. Your healthcare provider will determine the appropriate dose and form of meloxicam for you. It is important to take meloxicam exactly as prescribed by your healthcare provider and to follow all instructions on the prescription label.
Dosage for osteoarthritis
The recommended dosage of meloxicam for osteoarthritis is 7.5 mg once daily. Your healthcare provider may adjust your dose based on your individual needs and response to treatment.
It is important to take meloxicam with a full glass of water and to avoid lying down for at least 10 minutes after taking it to reduce the risk of stomach upset.
Do not exceed the recommended dose of meloxicam or take it for longer than prescribed, as this can increase the risk of side effects. If you have any questions about the appropriate dose of meloxicam for your condition, consult your healthcare provider.
Dosage for rheumatoid arthritis
The recommended starting dosage of meloxicam for rheumatoid arthritis is 7.5 mg once daily. Your healthcare provider may increase your dose to a maximum of 15 mg once daily based on your individual needs and response to treatment.
It is important to take meloxicam with a full glass of water and to avoid lying down for at least 10 minutes after taking it to reduce the risk of stomach upset.
Do not exceed the recommended dose of meloxicam or take it for longer than prescribed, as this can increase the risk of side effects. If you have any questions about the appropriate dose of meloxicam for your condition, consult your healthcare provider.
Dosage for juvenile idiopathic arthritis (JIA)
For the treatment of juvenile idiopathic arthritis (JIA), the recommended dosage of meloxicam is based on body weight. The recommended starting dose is 0.125 mg/kg once daily, up to a maximum of 7.5 mg/day. Your healthcare provider may adjust your dose based on your individual needs and response to treatment.
Meloxicam is not recommended for use in children under 2 years of age or weighing less than 60 kg (132 pounds).
It is important to take meloxicam with a full glass of water and to avoid lying down for at least 10 minutes after taking it to reduce the risk of stomach upset.
Do not exceed the recommended dose of meloxicam or take it for longer than prescribed, as this can increase the risk of side effects. If you have any questions about the appropriate dose of meloxicam for your child’s condition, consult your healthcare provider.
Special dosage considerations
There are several special dosage considerations that may apply to the use of meloxicam:
- Elderly patients: Elderly patients may be more sensitive to the effects of meloxicam and may require a lower dose. Your healthcare provider will determine the appropriate dose for you based on your individual needs.
- Patients with liver or kidney disease: Patients with liver or kidney disease may require a lower dose of meloxicam, as these conditions can affect the way the drug is metabolized and eliminated from the body.
- Patients taking other medications: Patients taking certain medications, such as blood thinners or diuretics, may require a lower dose of meloxicam or may need to avoid taking it altogether. Your healthcare provider will review your medication history and determine if meloxicam is safe for you to take.
- Pediatric patients: The dose of meloxicam for pediatric patients is based on body weight and is typically lower than the dose for adults. Meloxicam is not recommended for use in children under 2 years of age or weighing less than 60 kg (132 pounds).
It is important to follow all dosage instructions provided by your healthcare provider and to never exceed the recommended dose of meloxicam. If you have any questions or concerns about the appropriate dose of meloxicam for your condition, consult your healthcare provider.
Meloxicam warnings
There are several important warnings associated with the use of meloxicam:
- Cardiovascular risk: Meloxicam may increase the risk of serious cardiovascular events, such as heart attack or stroke, especially in patients with underlying cardiovascular disease or risk factors for cardiovascular disease. This risk may increase with prolonged use of meloxicam or at higher doses. Patients with cardiovascular disease or risk factors for cardiovascular disease should use meloxicam with caution and only under the direction of their healthcare provider.
- Gastrointestinal risk: Meloxicam may increase the risk of serious gastrointestinal events, such as bleeding or perforation of the stomach or intestines. This risk may be increased in patients who have a history of gastrointestinal ulcers or bleeding, are taking other medications that increase the risk of gastrointestinal bleeding, or are using meloxicam at high doses or for prolonged periods of time. Patients should take meloxicam with food and avoid taking it with alcohol or other medications that may increase the risk of gastrointestinal bleeding.
- Renal impairment: Meloxicam can cause or worsen renal impairment, especially in patients who are dehydrated, have preexisting renal disease, or are taking other medications that affect renal function. Patients with renal impairment should use meloxicam with caution and only under the direction of their healthcare provider.
- Hypersensitivity reactions: Meloxicam can cause serious hypersensitivity reactions, such as anaphylaxis or angioedema, especially in patients with a history of hypersensitivity to other NSAIDs or aspirin. Patients should stop taking meloxicam and seek immediate medical attention if they experience symptoms of a hypersensitivity reaction, such as difficulty breathing, swelling of the face or throat, or rash.
- Pregnancy and breastfeeding: Meloxicam is not recommended for use during pregnancy or breastfeeding, as it may harm the developing fetus or infant.
It is important to discuss any medical conditions or concerns with your healthcare provider before using meloxicam. Your healthcare provider will review your medical history and medication history to determine if meloxicam is safe and appropriate for you to use.
Allergy warning
Meloxicam may cause allergic reactions in some people. You should not take meloxicam if you have had an allergic reaction to meloxicam or any other NSAID medication in the past, such as aspirin or ibuprofen. Symptoms of an allergic reaction may include hives, rash, itching, difficulty breathing, or swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, seek immediate medical attention. Additionally, tell your healthcare provider about any allergies you have before starting treatment with meloxicam.
Liver damage warning
Meloxicam has been associated with liver damage in some patients, although this is a rare side effect. Patients with a history of liver disease or abnormal liver function tests should use meloxicam with caution and only under the direction of their healthcare provider. Symptoms of liver damage may include nausea, vomiting, abdominal pain, fatigue, dark urine, or yellowing of the skin or eyes. If you experience any of these symptoms, contact your healthcare provider immediately. Regular monitoring of liver function may be recommended during treatment with meloxicam, especially in patients who are using it for prolonged periods of time or at high doses.
Blood pressure warning
Meloxicam can increase blood pressure in some patients, especially those who already have high blood pressure. Patients with hypertension should use meloxicam with caution and only under the direction of their healthcare provider. Blood pressure should be monitored regularly during treatment with meloxicam, especially in patients who are using it for prolonged periods of time or at high doses. If you experience symptoms such as headaches, dizziness, or shortness of breath, contact your healthcare provider as these may be signs of elevated blood pressure.
Allergy warning
I’m sorry, I believe I provided information on the allergy warning earlier. Meloxicam may cause allergic reactions in some people. You should not take meloxicam if you have had an allergic reaction to meloxicam or any other NSAID medication in the past, such as aspirin or ibuprofen. Symptoms of an allergic reaction may include hives, rash, itching, difficulty breathing, or swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, seek immediate medical attention. Additionally, tell your healthcare provider about any allergies you have before starting treatment with meloxicam.
Multiorgan hypersensitivity/DRESS warning
Meloxicam use has been associated with a rare but serious condition known as drug reaction with eosinophilia and systemic symptoms (DRESS) or multiorgan hypersensitivity syndrome. This condition can affect multiple organs, including the liver, kidneys, lungs, and heart, and may be fatal if left untreated. Symptoms of DRESS may include fever, rash, swollen lymph nodes, facial swelling, and internal organ involvement. If you experience any of these symptoms, contact your healthcare provider immediately. Treatment with meloxicam should be discontinued if DRESS is suspected, and appropriate medical intervention should be initiated promptly.
Harm to developing fetus warning
Meloxicam should not be used during pregnancy, especially during the third trimester, as it may harm the developing fetus. Use of meloxicam during pregnancy may increase the risk of miscarriage, birth defects, and complications during delivery. If you are pregnant or planning to become pregnant, talk to your healthcare provider about alternative treatment options for your condition. Women who are breastfeeding should also use meloxicam with caution, as it may be excreted in breast milk and may harm the nursing infant.
Warnings for people with certain health conditions
Meloxicam should be used with caution in patients with certain health conditions, including:
- Cardiovascular disease: Meloxicam can increase the risk of cardiovascular events, such as heart attack or stroke, especially in patients with a history of cardiovascular disease or risk factors for cardiovascular disease. Patients with cardiovascular disease should use meloxicam with caution and only under the direction of their healthcare provider.
- Gastrointestinal disorders: Meloxicam can increase the risk of gastrointestinal bleeding or ulceration, especially in patients with a history of gastrointestinal disorders or those taking other medications that increase the risk of bleeding. Patients with a history of gastrointestinal bleeding or ulceration should use meloxicam with caution and only under the direction of their healthcare provider.
- Renal impairment: Meloxicam can impair kidney function and may exacerbate preexisting renal impairment. Patients with renal impairment should use meloxicam with caution and only under the direction of their healthcare provider.
- Asthma: Meloxicam can cause bronchospasm in some patients, especially those with a history of asthma. Patients with asthma should use meloxicam with caution and only under the direction of their healthcare provider.
- Bleeding disorders: Meloxicam can increase the risk of bleeding, especially in patients with bleeding disorders or those taking other medications that increase the risk of bleeding. Patients with bleeding disorders should use meloxicam with caution and only under the direction of their healthcare provider.
Warnings for other groups
Meloxicam should be used with caution in certain groups of patients, including:
- Elderly: Elderly patients may be more sensitive to the side effects of meloxicam, especially gastrointestinal bleeding, kidney impairment, and cardiovascular events. Elderly patients should use meloxicam with caution and only under the direction of their healthcare provider.
- Children: Meloxicam should not be used in children under 2 years of age, as its safety and efficacy in this age group have not been established. Children with juvenile idiopathic arthritis (JIA) should use meloxicam with caution and only under the direction of their healthcare provider.
- Smoking: Smoking may decrease the effectiveness of meloxicam and increase the risk of side effects, especially cardiovascular events. Patients who smoke should use meloxicam with caution and only under the direction of their healthcare provider.
- Alcohol use: Alcohol use can increase the risk of gastrointestinal bleeding and liver damage associated with meloxicam use. Patients who drink alcohol should use meloxicam with caution and only under the direction of their healthcare provider.
- Pregnancy and breastfeeding: Meloxicam should not be used during pregnancy, especially during the third trimester, as it may harm the developing fetus. Women who are breastfeeding should also use meloxicam with caution, as it may be excreted in breast milk and may harm the nursing infant.
Take as directed
It is important to take meloxicam exactly as prescribed by your healthcare provider. Follow all instructions on the prescription label and ask your doctor or pharmacist if you have any questions or concerns.
Meloxicam is usually taken once daily, with or without food. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
Do not take more or less of meloxicam than prescribed, and do not take it more frequently or for a longer period of time than recommended by your doctor. Doing so may increase the risk of side effects.
If you miss a dose of meloxicam, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
If you are unsure about how to take meloxicam, consult with your healthcare provider or pharmacist.
Important considerations for taking meloxicam
Here are some important considerations to keep in mind when taking meloxicam:
- Allergies: Tell your doctor if you are allergic to meloxicam or any other NSAIDs (such as aspirin or ibuprofen). Also, let your healthcare provider know if you have had any allergic reactions to other medications or have any other allergies.
- Medical history: Tell your doctor if you have a history of stomach or intestinal bleeding, liver or kidney disease, heart disease, high blood pressure, or asthma. Meloxicam may not be suitable for patients with certain medical conditions, and your doctor may need to adjust your dose or monitor you closely for side effects.
- Other medications: Inform your doctor or pharmacist about all the medications you are taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements. Some drugs may interact with meloxicam and increase the risk of side effects, while others may decrease its effectiveness.
- Use in pregnancy and breastfeeding: Meloxicam should not be used during pregnancy, especially during the third trimester, as it may harm the developing fetus. Women who are breastfeeding should also use meloxicam with caution, as it may be excreted in breast milk and may harm the nursing infant.
- Regular check-ups: Your healthcare provider will need to monitor you regularly while you are taking meloxicam to ensure that it is working properly and to check for side effects. Be sure to keep all your appointments with your doctor or healthcare provider.
- Overdose: If you suspect an overdose of meloxicam, seek immediate medical attention or call the Poison Control Center at 1-800-222-1222. An overdose of meloxicam can cause serious health problems, including stomach bleeding, kidney failure, and breathing difficulties.
General
Meloxicam is a medication used to treat pain and inflammation caused by conditions such as osteoarthritis, rheumatoid arthritis, and juvenile idiopathic arthritis. It is part of a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) and works by blocking the production of certain chemicals in the body that cause inflammation and pain.
When taking meloxicam, it is important to follow your doctor’s instructions carefully and take the medication exactly as prescribed. It may take several weeks for the full effects of meloxicam to be felt, so be patient and do not increase your dose or stop taking the medication without first consulting your doctor.
Like all medications, meloxicam can cause side effects, and it is important to be aware of these before starting treatment. Be sure to discuss any concerns or questions you have with your healthcare provider. Additionally, if you have any medical conditions or are taking other medications, make sure to inform your doctor or pharmacist, as this may affect the suitability of meloxicam for you.
Finally, if you experience any severe or concerning side effects while taking meloxicam, seek medical attention immediately or call your healthcare provider or the emergency services.
Storage
Meloxicam should be stored at room temperature, between 68°F to 77°F (20°C to 25°C), and away from moisture and heat. It should be kept in its original container with the lid tightly closed, and out of reach of children and pets.
Do not use meloxicam if it has expired or if the tablets appear to be damaged or discolored. If you have any questions about how to store meloxicam or concerns about the medication’s condition, contact your pharmacist or healthcare provider for advice.
Refills
If you are taking meloxicam regularly, you will likely need to refill your prescription from time to time. It is important to keep track of your medication supply and ensure that you have enough on hand to continue your treatment without interruption.
To avoid running out of medication, it is a good idea to order a refill when you have a week or two of meloxicam left. This will give your pharmacy sufficient time to process the refill and ensure that you have enough medication on hand.
Some pharmacies offer automatic refills or refill reminders to help you stay on top of your medication schedule. You can also set reminders on your phone or calendar to remind you to refill your prescription.
If you have any concerns or questions about refilling your meloxicam prescription, talk to your pharmacist or healthcare provider.
Travel
If you are traveling with meloxicam, it is important to ensure that you have enough medication on hand to last for the duration of your trip. This may require you to bring extra medication or to refill your prescription before you leave.
When traveling with medication, it is recommended that you keep it in its original container with the prescription label intact. This will help to prevent confusion and ensure that you have the correct medication and dosage information.
If you are traveling internationally, it is important to be aware of any restrictions on medications or prescription drugs in the countries you will be visiting. Some medications may be illegal or restricted in certain countries, so it is a good idea to research the laws and regulations before you leave.
If you have any concerns or questions about traveling with meloxicam, talk to your healthcare provider or pharmacist for advice. They can help you plan for your trip and ensure that you have the medication you need to stay healthy while you travel.
Clinical monitoring
If you are taking meloxicam, your healthcare provider may recommend regular clinical monitoring to ensure that the medication is working effectively and to monitor for any potential side effects.
This may include regular blood pressure checks, blood tests to monitor liver and kidney function, and regular physical exams. Your healthcare provider may also ask you about any symptoms or changes in your condition that you have noticed since starting the medication.
It is important to attend all scheduled appointments and to inform your healthcare provider if you experience any new or worsening symptoms while taking meloxicam. This can help to ensure that any potential issues are identified and addressed promptly.
If you have any concerns or questions about clinical monitoring while taking meloxicam, talk to your healthcare provider. They can provide guidance and advice on how to manage your condition and medication effectively.
Insurance
The cost of meloxicam can vary depending on your insurance coverage and the pharmacy where you fill your prescription. If you have health insurance, you may be able to have some or all of the cost of the medication covered.
To determine the exact cost of meloxicam with your insurance coverage, you can check with your insurance provider or with the pharmacy where you plan to fill your prescription. Some pharmacies may also offer discounts or coupons that can help to reduce the cost of the medication.
If you do not have health insurance or if your insurance does not cover the cost of meloxicam, you may be eligible for assistance through a patient assistance program. These programs are often offered by pharmaceutical companies and can provide financial assistance to individuals who meet certain criteria.
If you have any questions or concerns about the cost of meloxicam or insurance coverage, talk to your healthcare provider or pharmacist for advice. They can provide guidance on how to access the medication you need at an affordable cost.
Are there any alternatives?
Yes, there are other medications that can be used as alternatives to meloxicam for the treatment of pain and inflammation. Some other nonsteroidal anti-inflammatory drugs (NSAIDs) that are used for similar indications include ibuprofen, naproxen, and diclofenac.
There are also other types of medications that can be used for pain and inflammation, such as acetaminophen (Tylenol), tramadol, and opioid medications. However, these medications have different mechanisms of action and may have a higher risk of side effects or dependence.
Your healthcare provider can help determine which medication is most appropriate for you based on your individual medical history and condition. They can also help to weigh the benefits and risks of each medication and provide guidance on how to manage any potential side effects or interactions.